Author: Marc Bonten

  • Is the clinical trials enterprise broken?

    Is the clinical trials enterprise broken?

    Last week, I had the privilege to attend JAMA’s first ever summit in which two questions were addressed: ‘Is the clinical trials enterprise broken?’ and ‘How can it be fixed?’. The first question is rhetorical.

  • Antibiotics do more than causing resistance

    Antibiotics do more than causing resistance

    A couple of days ago in a study on continuous antibiotic prophylaxis in children with severe vesicoureteral reflux was published in the NEJM. An international open-label RCT with 292 kids enrolled over a period of (!) 7 years.

  • Female surgeons do better!/?

    Female surgeons do better!/?

    On my way to my 85-year-old dad who suffered from paralytic ileus after laparotomic hemicolectomy, I heard the following news: “Patients from female surgeons have less long-term postoperative complications (including death)“ (see: Wallis et al., JAMA Surg.). Is that what the study really revealed?